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Chromogenix

  • Commonly known as "chromogenix assay"
  • A complete suite of heamostasis & fibrinolytic solution based automated testing kits
  • Wide range of reagent kits, calibrators, substrates & bio reagents products

U-Prep

  • liquid based cytology (lbc) test for cervical cancer screening
  • Available in three variants -- manual, automated & semi automated
  • Complete customisation based on the customer needs

Product Catalogue

Packaging: Kit/120 tests
Method: Chromogenic
Type: Kit
Use: IVD

Chromogenix Coamatic® Factor VIII is a chromogenic assay kit for the photometric determination of factor VIII activity in plasma, such as when identifying factor VIII deficiency or monitoring patients on replacement therapy as well as for potency estimation of FVIII concentrates. This Factor VIII test kit fulfills the requirements of the European Pharmacopoeia for factor VIII concentrate testing. Co-lyophilization of reagents for convenient handling. Reliable tool for hemophilia classification. No interference from heparin levels up to 1.5 IU/ml. The Factor VIII kit has two measuring ranges plus validated and documented protocols for a wide range of instruments.

Products ❯ Hemostasis ❯ Coagulation Kits ❯ Factor VIII (FVIII) ❯ Chromogenix Coamatic® Factor VIII

Packaging: Vial/10IU
Method: Chromogenic
Type: Kit
Use: For Research Use Only

Chromogenix Antithrombin 10IU is for the determination of Heparin in plasma. Antithrombin in conjunction with heparine like substances is a potent inhibitor of thrombin, factor Xa, factor Xla and factor lXa. Antithrombin is prepared from human plasma and purified by affinity chromatography with an Heparine Sepharose gel according to the protocol of Miller-Andersson et al. (Thromb. Res. 5, 439-452, 1974).

Products ❯ Hemostasis ❯ Enzymes & Other Proteins ❯ Antithrombin ❯ Chromogenix Antithrombin 10IU

Chromogenix Antithrombin 25IU is a lyophilized powder prepared from human plasma after affinity chromatography on heparin-Sepharose gel. For the determination of Heparin. Pure preparation, does not contain stabilizer. Albumin-free.

Products ❯ Hemostasis ❯ Enzymes & Other Proteins ❯ Antithrombin ❯ Chromogenix Antithrombin 25IU

Packaging: Vial/71nkat
Method: Chromogenic
Type: Kit
Use: For Research Use Only

Chromogenix Factor Xa. 71 nkat, is for the determination of Heparin in plasma. Factor X is purified from a barium cytrate elution of bovine plasma and it is activated to FXa by a Russell’s Viper Venom matrix.

Products ❯ Hemostasis ❯ Enzymes & Other Proteins ❯ Factor Xa ❯ Chromogenix Factor Xa

Product Method / Application Packaging Use ?
Chromogenix S-2222™ Chromogenic Vial/25mg RUO
Chromogenix S-2238™ Chromogenic Vial/25mg RUO
Chromogenix S-2251™ Chromogenic vial/25mg RUO
Chromogenix S-2288™ Chromogenic Vial/25mg RUO
Chromogenix S-2302™ Chromogenic Vial/25mg RUO
Chromogenix S-2366™ Chromogenic Vial/25mg RUO
Chromogenix S-2403™ Chromogenic Vial/25mg RUO
Chromogenix S-2765™ Chromogenic Vial/25mg RUO
Packaging: Kit/200 tests
Method: Chromogenic
Type: Kit
Use: IVD

Chromogenix Coamatic® Heparin is a chromogenic assay kit for the quantitative determination of unfractionated heparin (UF Heparin) or low molecular weight heparin (LMW Heparin) in human citrated plasma using automated and microplate methods.

Chromogenic Substrate:

Enzymes are proteins that catalyze most of the chemical reactions that take place in the body. They make it possible for chemical reactions to occur at neutral pH and body temperature. The chemical compound upon which the enzyme exerts its catalytic activity is called a substrate. Proteolytic enzymes act on their natural substrates, proteins and peptides by hydrolyzing one or more peptide bond(s). This process is usually highly specific in the sense that only peptide bonds adjacent to certain amino acids are cleaved. Chromogenic substrates are peptides that react with proteolytic enzymes under the formation of color. They are made synthetically and are designed to possess a selectivity similar to that of the natural substrate for the enzyme. Attached to the peptide part of the chromogenic substrate is a chemical group which when released after the enzyme cleavage gives rise to color. The color change can be followed spectrophotometrically and is proportional to the proteolytic activity. Chromogenic substrate technology was developed in the early 1970s, and has since then become a tool of substantial importance in basic research. The majority of chromogenic substrate applications are found in various clinical fields. In particular they have been used to generate fundamental knowledge of the mechanisms regulating blood coagulation and fibrinolysis. Furthermore, products based on chromogenic substrate technology have brought a new generation of diagnostics into the clinical laboratory.

Products ❯ Hemostasis ❯ Anticoagulation Monitoring Kits ❯ Heparin Kits ❯ Chromogenix Coamatic® Heparin

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2222™ is a chromogenic substrate for Factor Xa. It is also very sensitive to trypsin. The substrate has been used for the determination of:

  • Factor X in plasma
  • Factor Xa in plasma
  • Factor Xa inhibitor in plasma
  • Heparin in plasma
  • Factor VIII in plasma
  • Coagulating enzyme from horseshoe crab plasma
  • Trypsin in duodenal fluid

The substrate is also sensitive to subtilisin, acrosin and Factor XIIa but insensitive to most other enzymes tested, e.g. Factor IXa, kallikrein (glandular and plasma) and papain-like enzymes.

Products ❯ Hemostasis ❯ Enzymes & Other Proteins ❯ Factor Xa ❯ Chromogenix Factor Xa

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2238™ is a chromogenic substrate for thrombin. The substrate has been used for the determination of:

  • Factor X in plasma
  • Prothrombin in plasma
  • Antithrombin in plasma
  • Platelet factor 3 in plasma
  • Heparin in plasma

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Prothrombin (FII) ❯ Chromogenix S-2238™

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2251™ is a chromogenic substrate for plasmin and streptokinase-activated plasminogen. The substrate has been used for the determination of:

  • Antithrombin in plasma
  • Plasminogen in plasma

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Plasminogen-Streptokinase (Plg) ❯ SK) ❯ Chromogenix S-2251™

Chromogenix S-2302™ is a chromogenic substrate for plasma kallikrein. The substrate has been used for the determination of:

  • Prekallikrein in plasma
  • Kallikrein inhibitors in plasma
  • FXII in plasma
  • Kallikrein-like activity in plasma
  • Prekallikrein activator in albumin and immunoglobulin preparations

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Prekallikrein ❯ Chromogenix S-2302™

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2288™ is a chromogenic substrate sensitive to a broad spectrum of serine proteases. The substrate has been used for the determination of Tissue Plasminogen Activator in purified preparations.

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Tissue Plasminogen Activator (tPA) ❯ Chromogenix S-2288™

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2366™ is a chromogenic substrate for factor XI and activated protein C. The substrate can be used for the determination of purified enzyme preparations as well as of Protein C and FXI in plasma.

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Hirudin ❯ Chromogenix S-2366™

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2765™ is a chromogenic substrate for determination of Factor Xa activity. It is also very sensitive to trypsin.
S-2765™ is suitable for measuring FXa inhibition in heparin anti-Xa assays and antithrombin anti-Xa assays.

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Trypsin ❯ Chromogenix S-2765™

Packaging: Vial/25mg
Method: Chromogenic
Type: Substrate
Use: For Research Use Only

Chromogenix S-2403™ is a chromogenic substrate for plasmin and streptokinase-activated plasminogen.

Products ❯ Hemostasis ❯ Chromogenic Substrates ❯ Plasminogen-Streptokinase (Plg) ❯ SK) ❯ Chromogenix S-2403™

For Customized Special Orders for Enterprises, Research Institutes & NGO's

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